The mean total PHQ-9 and PHQ-2 scores were 8.47 ± 6.17 and 2.42 ± 1.86, respectively, and using a cut-off value of 10 (for PHQ-9) and 3 (for PHQ-2), the prevalence of depressive symptoms was 38.6 and 43.6%, respectively. Convergent validity was evaluated by relationship with WHO-5, HADS and GAD-7.
Factor structure and internal consistency of PHQ-9 were examined via confirmatory factor analysis (CFA) and Cronbach’s alpha, respectively. In this cross-sectional study, a total of 539 patients with infertility from a referral infertility clinic in Tehran, Iran completed the PHQ-9, along with other relevant scales: the WHO-five Well-being Index (WHO-5), the Hospital Anxiety and Depression Scale (HADS), and the Generalized Anxiety Disorder-7 (GAD-7). The aim of the present study was to examine the reliability and validity of the PHQ-9 and PHQ-2 in patients with infertility. These scales have not been validated in patients with infertility. PHQ-2) are widely used measures of depressive symptoms.
The Patient Health Questionnaire-9 (PHQ-9) and its ultra-brief version (i.e. Depression in patients with infertility often goes undiagnosed and untreated.